Table 1.

Physical characteristics of uncoated and coated CS-NPs measured by Zetasizer (mean ± SD, n = 3).

Optimized formulations	Particle size (nm) ± SD	Polydispersity (PDI) ± SD	Zeta potential (mV) ± SD
Uncoated CS-NPs	298.11 ± 20.15	0.356 ± 0.034	34.3 ± 5.2
CS-NPs coated with HA	390.84 ± 27.28	0.123 ± 0.041	−36.1 ± 5.4
CS-NPs coated with ALG	843.42 ± 70.54	0.566 ± 0.054	−64.2 ± 8.2