Fig. 2.

ASIC2 promotes invasion of CRC cells under acidosis. a SW480 and HCT116 cells expressing ASIC2 or vector were cultured in pH 6.5 medium for 24 h. The invasion ability was measured by Transwell invasion assay. b The invasion ability of SW620 and HT29 cells transfected with lentivirus expressing shASIC2 or scramble cultured in pH 6.5 medium for 24 h was measured by Transwell invasion assay. *p < 0.05, **p < 0.01