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. 2017 Sep 19;36:130. doi: 10.1186/s13046-017-0599-9

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — High expression of ASIC2 predicts poor outcomes of CRC patients. a Immunohistochemistry analysis was performed on paraffin-embedded tissues from 147 patients with CRC using a primary antibody against ASIC2. Representative images of ASIC2 staining in adjacent tissue (left panel) and carcinoma (right panel) are shown in CRC tissues (middle panel). b IHC scores of ASIC2 in primary cancer and adjacent tissues. ASIC2 expression was significantly increased in primary cancer. c Overall survival rates of CRC patients with high or low expression of ASIC2 were estimated by Kaplan-Meier analysis