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. 2017 Sep 19;15:175. doi: 10.1186/s12957-017-1244-y

Table 3.

The NSCLC highly saturated pathways by targets of upregulated (red) and downregulated (blue) microRNAs

Term Count p value Fold enrichment Benjamini FDR
GO:0000122~negative regulation of transcription from RNA polymerase II promoter 56 4.86E−10 2.518139934 1.30E−06 8.63E−07
GO:0045944~positive regulation of transcription from RNA polymerase II promoter 62 9.15E−08 2.06555926 1.22E−04 1.63E−04
GO:0060021~palate development 13 3.25E−06 5.557193787 0.002893 0.005773
GO:0006366~transcription from RNA polymerase II promoter 36 8.39E−06 2.292001365 0.005597 0.014915
GO:0008284~positive regulation of cell proliferation 33 2.87E−05 2.258248746 0.015224 0.050944
GO:0001974~blood vessel remodeling 8 7.27E−05 7.523585434 0.03191 0.129182
GO:0036092~phosphatidylinositol-3-phosphate biosynthetic process 9 1.02E−04 6.045738295 0.038266 0.181279
GO:0006351~transcription, DNA-templated 88 1.35E−04 1.483903889 0.044245 0.24022
GO:0006357~regulation of transcription from RNA polymerase II promoter 29 1.69E−04 2.18433616 0.049011 0.300012
GO:0045944~positive regulation of transcription from RNA polymerase II promoter 151 8.98E−10 1.635197256 4.34E−06 1.70E−06
GO:0045893~positive regulation of transcription, DNA-templated 80 7.28E−06 1.658786271 0.017456 0.013808
GO:0006366~transcription from RNA polymerase II promoter 78 2.54E−05 1.614188342 0.024278 0.048167
GO:0048013~ephrin receptor signaling pathway 22 3.15E−05 2.736997347 0.025043 0.059642
GO:0007264~small GTPase mediated signal transduction 45 2.37E−05 1.941381916 0.028286 0.044989
GO:0090190~positive regulation of branching involved in ureteric bud morphogenesis 10 2.05E−05 5.631142867 0.032546 0.038909
GO:0032331~negative regulation of chondrocyte differentiation 9 6.40E−05 5.664267237 0.043258 0.121289
GO:0007010~cytoskeleton organization 32 7.75E−05 2.126543393 0.045758 0.146799