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. 2017 Sep 19;12:68. doi: 10.1186/s13024-017-0202-z

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Effect of S1R knockout on rod electrophysiological responses in rd10 mice. Rod ERG recording was performed with scotopic flash stimulation at indicated flash intensities and time points, as described in Methods. a. Average plot of a-wave amplitudes of rd10/S1R^+/+ mice and rd10/S1R^-/- mice. The dashed green line serves as a reference for comparison between two plots. b. Comparison of a-wave amplitude averages (30 cd.s/m²) in the presence and absence of S1R. c. Separately plotted average b-wave amplitudes of rd10/S1R^+/+ and rd10/S1R^-/- mice. d. Comparison of b-wave amplitude averages (30 cd.s/m²) in the presence and absence of S1R. ERG a-wave is the downward deflected negative response; b-wave is from the a-wave peak to positive response peak. Quantification: Mean ± SE, n = 5–7 mice; *P < 0.05