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. Author manuscript; available in PMC: 2017 Dec 7.
Published in final edited form as: Sci Transl Med. 2017 Jun 7;9(393):eaal1669. doi: 10.1126/scitranslmed.aal1669

Fig. 3.

Fig. 3

Liver-specific deletion of Abcc6 does not phenocopy constitutive ablation of Abcc6 in mice.

Micro-CT scans of the muzzle to evaluate the extent of vibrissae fibrous capsule calcification were obtained at 20 weeks (A) and 1 year (D) of age. (B and E) Quantification of ectopic calcification from micro-CT images. A one-way ANOVA with Tukey’s honest significance difference post hoc analysis was performed. One-way ANOVA: (B) P = 2.2 × 10−16; (E) P = 4.68 × 10−11. P values of post hoc comparisons are indicated in the figure. (C) Visualization and confirmation of Cre-targeted tissues and cell types using the RosamTmG reporter mouse line. All cells that are successfully recombined transition from expression of membrane Tomato (mT; red fluorescence) to green fluorescent protein (mG; green fluorescence). Representative images are shown.