Fig. 3.

Interactions module. The displayed data are from wild type protein p53 (1TSR.A) and its variants were selected using 70% identity and the PSI-BLAST alignment method. a All residues that establish hydrophobic interactions are colored in rose. The alignment position 50, which corresponds to mutation Val143Ala, was highlighted. b Hydrophobic interactions for mutation Val143Ala. The alignment position (column) 50 was selected to show only its hydrophobic interactions. The zoom of 30% was used to display short and long distance interactions. c 3D molecular representation of interactions for Val143 from protein p53 (1TSR.A). d Graphs (2D schematic representation) of p53 (1TSR.A) interactions for residue Val143