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. 2017 Sep 13;18(Suppl 10):403. doi: 10.1186/s12859-017-1789-3

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© The Author(s) 2017

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License(http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Topological properties module. The degree centrality measure for wild type protein p53 (1TSR.A) and its variants selected using 70% identity and the PSI-BLAST alignment method. Network centralities are displayed in a heatmap based on the sequence alignment visualization