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Mutations (nsSNPs) in the p53 (PDBid 1TSR) core domain that were experimentally characterized
| Mutant categories | Mutations |
|---|---|
| No structural effects | Arg273His |
| Weakly/locally destabilising | Gly245Ser |
| Arg249Ser | |
| Arg248Ala | |
| Highly destabilising/global unfolding | Cys242Ser |
| His168Arg | |
| Val143Ala | |
| Ile195Thr |
