Table 3.
Mouse models of cancer-associated hypercalcemia.
| Type of model | Model Name and Tumor Origin | Strain | References |
|---|---|---|---|
| Allogenic | HSDM1 fibrosarcoma | Swiss albino mice | [119] |
| CE mammary carcinoma | BALB/cfC3H | [120,121] | |
| 5T2MM and 5T33MM multiple myeloma | C57BL/KalwRiJ | [122,123] | |
| Transgenic | Tax+ lymphoma/leukemia | Tax+ C57B6/SJL | [124] |
| Infusion | PTHrP, IL-1, IL-11, TNF-α | - | [50,125,126] |
| Induction | Cutaneous administration of dimethylbenzanthracene induced squamous cell carcinoma | CD1 mice | [50,118] |
| Xenograft | Lung cancer | Nude mice | [127,128,129] |
| Squamous cell carcinoma | [128,130] | ||
| Renal cell carcinoma | [131,132] | ||
| Urothelial cancer | [133] | ||
| Esophageal carcinoma | [134,135] | ||
| Melanoma | [136,137] | ||
| Mammary cancer | [138] | ||
| Pancreatic cancer | [139] | ||
| Colon cancer | [140,141] | ||
| Ovarian cancer | [142] | ||
| Adult T-cell leukemia/lymphoma | SCID, NOD/scid | [143,144,145] | |
| Multiple myeloma | [146,147] | ||
| Ovarian cancer | [148] |