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. 2017 Sep 1;6:e23708. doi: 10.7554/eLife.23708

Table 3. Multivariable predictors for time to recurrent blood-stage infection with Plasmodium species by qPCR.

Variable P. vivax P. falciparum P. malariae P. ovale
AHR* CI95 p-value AHR* CI95 p-value AHR* CI95 p-value AHR* CI95 p-value
PQ treatment 0.18 0.13–0.25 <0.001 0.73 0.52–1.02 0.064 0.51 0.22–1.19 0.121 0.31 0.12–0.75 0.010
Age 0.95 0.87–1.04 0.247 1.05 0.94–1.17 0.361 0.98 0.75–1.29 0.905 0.96 0.74–1.26 0.793
LLIN use at enrolment 0.62 0.39–0.98 0.043 0.84 0.49–1.44 0.531 1.33 0.33–6.09 0.715 0.95 0.26–3.43 0.936
Hb at enrolment (g/dl) 0.88 0.80–0.98 0.019 0.90 0.80–1.02 0.099 0.83 0.61–1.12 0.224 0.92 0.66–1.28 0.634
Village
 Albinama (ref) 1 1 1 1
 Amahup 0.45 0.29–0.71 0.001 0.58 0.31–1.11 0.101 0.34 0.07–1.79 0.205 2.83 0.29–27.48 0.370
 Balanga 2.15 1.40–3.31 <0.001 1.81 0.99–3.30 0.054 0.92 0.24–3.60 0.910 7.74 0.85–70.45 0.070
 Balif 1.00 0.66–1.54 0.983 0.60 0.30–1.19 0.145 0.24 0.03–2.07 0.193 4.60 0.51–41.41 0.173
 Bolumita 3.34 2.09–5.33 <0.001 4.73 2.69–8.30 <0.001 1.21 0.34–4.31 0.770 19.43 2.19–172.37 0.008
 Numangu 0.83 0.44–1.59 0.583 2.29 1.17–4.50 0.015 0.82 0.15–4.53 0.823 3.17 0.19–52.41 0.420
Infection status at enrolment (by qPCR)
 Uninfected (ref) 1 1 1 1
P. vivax 1.27 0.91–1.78 0.165 1.37 0.86–2.20 0.186 0.92 0.20–4.18 0.913 2.17 0.68–6.97 0.192
P. falciparum 1.36 0.84–2.19 0.205 1.56 0.86–2.82 0.145 3.54 0.85–14.72 0.083 1.25 0.26–5.90 0.779
P. malariae 0.83 0.38–1.85 0.655 0.99 0.38–2.56 0.977 6.35 1.31–30.81 0.022 1.58 0.17–14.30 0.676
 Mixed P.f. or P.v. 1.74 1.14–2.65 0.010 2.08 1.25–3.48 0.005 3.37 0.88–12.90 0.076 2.03 0.55–7.53 0.287

* AHRs were modeled using Cox proportional hazard regression.

† Mixed infection including P. falciparum or P. vivax infection in conjunction with one or more other Plasmodium spp.

PQ: Primaquine; LLIN: long-lasting insecticide-treated net; Hb: haemoglobin.