. 2017 Sep 1;6:e23708. doi: 10.7554/eLife.23708

Table 4. Multivariable predictors of Pv- and Pf-_molFOB per follow-up interval.

Model predictions from this model were used for mapping _molFOB in Figure 3A.

Variable	P. vivax						P. falciparum
	PQ arm			Placebo arm			Combined arms
	IRR^*	CI₉₅	p-value	IRR^*	CI₉₅	p-value	IRR^*	CI₉₅	p-value
PQ treatment	n.a.^†	n.a.	n.a.	n.a.	n.a.	n.a.	0.89	0.65–1.22	0.474
New P. falc. infections in interval^‡	1.32	0.92–1.89	0.134	1.10	0.85–1.42	0.466	n.a.	n.a.	n.a.
New P. vivax infections in interval^‡	n.a.	n.a.	n.a.	n.a.	n.a.	n.a.	1.15	0.97–1.36	0.100
Age	0.86	0.74–1.01	0.059	0.95	0.87–1.04	0.305	1.03	0.92–1.14	0.640
LLIN use at enrolment	0.96	0.51–1.79	0.897	0.62	0.43–0.91	0.013	1.07	0.7–1.62	0.755
Hb at enrolment (g/dl)	0.85	0.72–1.01	0.063	0.91	0.85–0.99	0.025	0.85	0.75–0.97	0.013
Village
Albinama (ref)	1			1			1
Amahup	0.02	0–0.11	<0.001	0.56	0.34–0.91	0.020	0.52	0.25–1.07	0.074
Balif	0.85	0.4–1.8	0.664	1.74	1.16–2.61	0.007	1.81	0.98–3.35	0.059
Balanga	0.28	0.1–0.82	0.020	1.13	0.73–1.73	0.590	0.75	0.37–1.52	0.423
Bolumita	1.52	0.73–3.17	0.268	2.67	1.83–3.9	<0.001	6.05	3.32–11.05	<0.001
Numangu	0.5	0.15–1.68	0.264	0.76	0.4–1.43	0.394	2.8	1.39–5.64	0.004
Study Day
Day 0–35 (ref)	1			1			1
Day 36–80	1.37	0.54–3.48	0.509	1.99	1.39–2.84	<0.001	2.42	1.44–4.07	0.001
Day 81–175	1.34	0.57–3.12	0.503	0.89	0.61–1.3	0.538	1.13	0.7–1.84	0.616
Day > 175	0.65	0.25–1.69	0.374	0.56	0.38–0.83	0.004	0.87	0.48–1.56	0.643

*IRRs were modeled per sampling interval using negative binomial generalized estimating equations allowing for repeated visits with log-link and an exchangeable correlation structure.

† n.a., not applicable.

‡_molFOB in the follow-up interval (time-varying covariate).

PQ: Primaquine; LLIN: long-lasting insecticide-treated net; Hb: haemoglobin.

Table 4. Multivariable predictors of Pv- and Pf-molFOB per follow-up interval.

Table 4. Multivariable predictors of Pv- and Pf-_molFOB per follow-up interval.