Table 5. Multivariable predictors for time to P. vivax and P. falciparum clinical episodes.

Model predictions from this model were used for mapping the relative risk of clinical malaria episodes in Figure 3C and D.

Variable	P. vivax			P. falciparum
	AHR*	CI95	p-value	AHR*	CI95	p-value
PQ treatment	0.76	0.34–1.68	0.497	1.79	1.05–3.03	0.031
P. vivax molFOB‡	1.07	1.04–1.09	<0.001	n.a.	n.a.	n.a.
P. falciparum molFOB‡	n.a.	n.a.	n.a.	1.15	1.11–1.21	<0.001
Age	0.62	0.46–0.84	0.002	0.98	0.85–1.13	0. 799
LLIN use at enrolment	0.84	0.24–2.88	0.778	0.44	0.22–0.87	0.018
Hb at enrolment (g/dl)	0.95	0.74–0.67	0.668	0.85	0.71–1.01	0.070
Village
Albinama (ref)	1			1
Amahup	0.89	0.23–3.46	0.871	0.65	0.20–2.08	0.465
Balif	1.48	0.45–4.86	0.518	1.26	0.50–3.14	0.626
Balanga	0.85	0.21–3.53	0.827	1.39	0.59–3.30	0.455
Bolumita	0.99	0.24–4.03	0.987	1.32	0.58–3.03	0.508
Numangu	1.00	0.23–4.31	0.997	4.29	2.06–8.97	<0.001
Infection status at enrolment (by qPCR)
Uninfected (ref)	1			1
P. vivax	0.77	0.29–2.07	0.608	1.64	0.91–2.95	0.101
P. falciparum	1.74	0.59–5.11	0.316	0.97	0.34–2.77	0.954
Mixed P.f. or P.v.	1.59	0.56–4.50	0.381	1.24	0.57–2.68	0.582

* AHRs were modeled using multiple failure Cox proportional hazard regression.

† n.a., not applicable.

‡ Average _molFOB until the time of failure (time-varying covariate).

PQ: Primaquine; LLIN: long-lasting insecticide-treated net; Hb: haemoglobin.