Table 6. Multivariable predictors for odds of P. falciparum clinical episodes.
P. falciparum episode | |||
---|---|---|---|
Variable | OR* | CI95 | p-value |
PQ treatment | 1.42 | 0.80–2.52 | 0.226 |
P. vivax qPCR positive† | 0.35 | 0.15–0.78 | 0.011 |
P. falciparum molFOB‡ | 1.21 | 1.10–1.34 | <0.001 |
Age | 0.93 | 0.80–1.09 | 0.370 |
LLIN at enrolment | 0.37 | 0.16–0.83 | 0.016 |
Hb (g/dl) at enrolment | 0.88 | 0.70–1.11 | 0.292 |
Village | |||
Albinama (ref) | 1 | ||
Amahup | 0.41 | 0.12–1.39 | 0.154 |
Balif | 0.9 | 0.26–3.08 | 0.870 |
Balanga | 1.19 | 0.42–3.39 | 0.747 |
Bolumita | 1.48 | 0.42–5.17 | 0.540 |
Numangu | 4.17 | 1.64–10.58 | 0.003 |
Study Day | |||
Day 0–80 | 1 | ||
Day 81–175 | 0.99 | 0.51–1.91 | 0.972 |
Day > 175 | 0.83 | 0.39–1.75 | 0.629 |
* ORs were modeled using a binomial generalized estimating equation with logit link function using an exchangeable correlation structure.
† Determined as P. vivax positive at the same or previous sampling visit.
‡molFOB in the follow-up interval (time-varying covariate).
PQ: Primaquine; LLIN: long-lasting insecticide-treated net; Hb: haemoglobin.