Figure 7. Behavioral PLS analysis on value- and salience-coding BOLD response and two measures of impulsivity.

Two orthogonal components were identified. The first component (A) captured the relationship between value signal from vmPFC, salience signals from anterior insula and dACC, and inhibitory control scores on the Flanker task. The second component (B) captured the relationship between value signals from mSNc and VS, and the AUC measure of delay discounting. Value and salience BOLD signals were derived from the gambling task. Note: for delay-discounting lower AUC indicates greater impulsivity. (AUC: area under the curve). In the leftmost panel, blue color of the bars indicates a reliable contribution (z > 1.96) as determined by the bootstrap procedure. Error bars in the middle panel represent 95% confidence intervals derived from bootstrap resampling. See text for abbreviations.

Figure 7—figure supplement 1. Correlation analysis between value and salience BOLD response and two measures of impulsivity.

Decisional impulsivity (A) measured by AUC of Delay-Discounting task was associated with value-related BOLD response in medial SNc and VS. Motor impulsivity (B) measured by Flanker Inhibitory control task was correlated with salience-related BOLD response in anterior Insula and dACC. The red stars indicate significant correlations after Holm–Bonferroni multiple comparison correction using a p-value=0.05.