Table 1.
Demographic data of subjects in the present study and in other recent publications on predictive HD testing
| Present study | Bernhardt et al. (2009) | Panas et al. (2011) | Dufrasne et al. (2011) | Sizer et al. (2012) | Wedderburn et al. (2013) | Scuffham and MacMillan (2014) | |
|---|---|---|---|---|---|---|---|
| Country | Italy | Germany | Greece | Canada | South Africa | Australia (Western) | Australia (Queensland) |
| Study period | 1993–2014 | 1993–2004 | 1995–2008 | 1994–2008 | 1998–2006 | 1993–2012 | 2006–2010 |
| Number of applicants | 299 | 478 | 256b | 181 | 57 | 466 | 152 |
| Average age (years) | 35.4 | 35.0 | 33.8b | 36.4b | 30.0 | 48.9 | 39.3 |
| Gender: females (%) | 54.8 | 57.0 | 54.7b | 61.9 (57.0b) | 66.7 | 57.6 | 54.5 |
| Applicants married or in a stable relationship (%) | 66.2 | 73.8 | – | 70.4b | – | – | 70.2 |
| Applicants with children (%) | 41.1 | 44.0 | – | 57.0b | 43.9 | – | 58.5 |
| Applicants with 50% risk (%) | 85.3 | 92.0 | – | 98.5 | – | – | 82.3 |
| Protocol completed (%) | 56.9 (60.3a) | 52.0 | 100.0b | 74.6 | 66.7 | 80.0 | 62.5 |
| Positive test result (CAG≥36) | 37.6 | – | 48.0 | 42.2 | 36.9 | 37.0 | 54.6 |
a
Data on 282 applicants after excluding symptomatic patients who were referred to other specialists without taking the test (n = 17).
b
Data given only about patients who completed the protocol for predictive testing.