Table 4.
HD symptoms and signs observed in affected relatives and considered the most disabling ones
| Symptom/Sign | Total (n = 120) | Gender | Protocol completed | Lived with an affected relative | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Males (n = 50) | Females (n = 70) | P‐value | Yes (n = 70) | No (n = 50) | P‐value | Yes (n = 86) | No (n = 17) | P‐value | ||
| Involuntary movements | 102 (85.0) | 43 (86.0) | 59 (84.3) | ns | 58 (85.3) | 44 (84.6) | ns | 72 (83.7) | 15 (93.8) | ns |
| Loss of self‐sufficiency | 56 (46.7) | 20 (40.0) | 36 (51.4) | ns | 35 (51.5) | 21 (40.4) | ns | 47 (54.7) | 8 (50.0) | ns |
| Personality changes | 37 (30.8) | 10 (20.0) | 27 (38.6) | 0.030 | 22 (32.4) | 15 (28.8) | ns | 32 (37.2) | 3 (18.8) | ns |
| Aggressiveness | 34 (28.3) | 10 (20.0) | 24 (34.3) | ns | 23 (33.8) | 11 (21.2) | ns | 31 (36.0) | 2 (12.5) | ns |
| Depression | 29 (24.2) | 7 (14.0) | 22 (31.4) | 0.028 | 17 (25.0) | 12 (23.1) | ns | 24 (27.9) | 2 (12.5) | ns |
| Cognitive decline | 27 (22.5) | 12 (24.0) | 15 (21.4) | ns | 17 (25.0) | 10 (19.2) | ns | 19 (22.1) | 4 (25.0) | ns |
ns, not significant.