Table 2.
Mean value changes in the study
| Baseline | 6 months | 12 months | Significant changes | |
|---|---|---|---|---|
| BCVA | 46.7 ± 16.47 ETDRS letters (20–73) | 60.3 ± 13.7 ETDRS letters (20–82) | 59.1 ± 17.2 ETDRS letters (20–80) | p < 0.001, F = 4.168 |
| CRT | 446.1 ± 121.3 μm (282–708) | 389 ± 139.7 μ (130–715) | 346 ± 132.8 μ (139–653) | p = 0.001, t = −4.351 |
| TMV | 9.93 ± 1.56 mm3 (6.68–13.9) | 9.42 ± 1.6 mm3 (6.85–13.18) | 9.12 ± 14.56 mm3 (6.67–14.56) | p = 0.003, t = −3.694 |
| Mean preservation of the ellipsoid zone | 826.8 ± 450.5 μm | 917.79 ± 451.90 μm | 935.64 ± 467,9 μm | p = 0.009, F = 2.766 |
| Mean preservation of the ELM layer | 662.7 ± 498,2 μm | 712.81 ± 432.2 μm | 763.64 ± 517,78 μm | p = 0.002, F = 3.981 |
| Mean dR P1 wave in R1 | 30.6 ± 15.4 nV/deg2 (9.5–63.7) | 40.5 ± 22.3 nV/deg2 (9.8–93.7) | 47.9 ± 24.9 nV/deg2 (5.6–100) | p < 0.001, F = 4.528 |
| Mean dR P1 wave in R2 | 18.7 ± 6.4 nV/deg2 (7.6–34.4) | 30.5 ± 5.3 nV/deg2 (7.6–39) | 25.9 ± 3.7 nV/deg2 (1.4–35.9) | p = 0.05, F = −1.137 |
| Mean dR P1 wave in R3 | 15.3 ± 7.8 nV/deg2 (0.8–44.5) | 17.2 ± 10.7 nV/deg2 (5.54–47.9) | 15.4 ± 13 nV/deg2 (4.32–79.8) | p = 0.91, F = −0.063 |
| Mean IT-P1 R1 | 44.07 ± 7.3 ms (33.6–50.2) | 42.2 ± 9.1 ms (19.7–50.2) | 41.9 ± 8.9 ms (16.8–50.2) | p = 0.26, F = 1.128 |
| Mean IT-P1 R2 | 46.4 ± 3.8 ms (32.5–50.2). | 45.5 ± 7.1 ms (19.7–67.4) | 44.5 ± 10.2 ms (19.7–79.8) | p = 0.32, F = 0.948 |
| Mean IT-P1 R3 | 44.3 ± 5.1 ms (20.1– 50.2) | 43.29 ± 5.16 ms (20.2–50.2) | 43.86 ± 5.25 ms (23.6–50.2) | p = 0.74, F = 0.353 |
BCVA best-corrected visual acuity, CRT central retinal thickness, TMV total macular volume, ellipsoid zone internal segment/external segment layer, ELM external limiting membrane, F ANOVA function