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. 2017 Jul 8;5(3):224–234. doi: 10.14218/JCTH.2017.00014

Table 3. 18F-FDG-PET for predicting aggressive histopathologic features in liver transplant patients with HCC.

Authors n PET−/PET+ (n) Predicting poor grading (Sensitivity/Specificity/PPV/NPV/Accuracy) Predicting MVI (Sensitivity/Specificity/PPV/NPV/Accuracy)
Yang et al.70 38 25/13 47.8%/85.7%/84.6%/50%/60.5% 77.8%/79.3%/53.8%/92%/78.9%
Kornberg et al.72 42 26/16 83.3%/69.4%/31.3%/96.1%/71.4% 82.3%/92%/87.5%/88.5%/88.1%
Kornberg et al.73 91 36/19 76.4%/70.3%/37.1%/92.9%/71.4% 81.1%/90.7%/85.7%/87.5%/86.8%
Lee et al.75 191 136/55 37.3%/81.7%/75.5%/46%/51.3% 45.4%/83.9%/66%/69.1%/67.5%
Lee et al.76 280 190/90 (beyond MC)
52.6%/62.3%/61.2%/53.8%/57.1%
(beyond MC)
58.4%/68.6%/67.2%/60%/63.3%
Hsu et al.78 147 117/30 100%/80.7%/6.7%/100%/81% 30.3%/85.7%/56.7%/66.7%/64.6%

Abbreviations: MC, Milan criteria; NPV, negative predictive value; PET, positron emission tomography; PPV, positive predictive value.