Table 3. 18F-FDG-PET for predicting aggressive histopathologic features in liver transplant patients with HCC.
Authors | n | PET−/PET+ (n) | Predicting poor grading (Sensitivity/Specificity/PPV/NPV/Accuracy) | Predicting MVI (Sensitivity/Specificity/PPV/NPV/Accuracy) |
Yang et al.70 | 38 | 25/13 | 47.8%/85.7%/84.6%/50%/60.5% | 77.8%/79.3%/53.8%/92%/78.9% |
Kornberg et al.72 | 42 | 26/16 | 83.3%/69.4%/31.3%/96.1%/71.4% | 82.3%/92%/87.5%/88.5%/88.1% |
Kornberg et al.73 | 91 | 36/19 | 76.4%/70.3%/37.1%/92.9%/71.4% | 81.1%/90.7%/85.7%/87.5%/86.8% |
Lee et al.75 | 191 | 136/55 | 37.3%/81.7%/75.5%/46%/51.3% | 45.4%/83.9%/66%/69.1%/67.5% |
Lee et al.76 | 280 | 190/90 | (beyond MC) 52.6%/62.3%/61.2%/53.8%/57.1% |
(beyond MC) 58.4%/68.6%/67.2%/60%/63.3% |
Hsu et al.78 | 147 | 117/30 | 100%/80.7%/6.7%/100%/81% | 30.3%/85.7%/56.7%/66.7%/64.6% |
Abbreviations: MC, Milan criteria; NPV, negative predictive value; PET, positron emission tomography; PPV, positive predictive value.