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. 2017 May 30;5(3):272–276. doi: 10.14218/JCTH.2017.00010

Fig. 1. Proposed algorithm after screening for HBV infection in prisoners.

Fig. 1.

A subject with anti-HBs and IgM anti-HBc negativity, but HBsAg and anti-HBc positivity is chronically infected. A subject with anti-HBs negativity, and HBsAg and IgM anti-HBc positivity is acutely infected. A subject with HBsAg negativity, and anti-HBc and anti-HBs positivity is immune due to natural infection. A subject with only anti-HBs positivity is immune due to HB vaccination. A subject with all markers showing negativity is susceptible to infection. Anti-HBc positivity, in the presence of HBsAg and anti-HBs negativity, can be found in the following cases: 1) resolved infection; 2) false positivity of anti-HBc; 3) resolving acute infection; and 4) occult infection. It could be useful to evaluate other markers (HBeAg, anti-HBe) and determine the viremia (HBV-DNA) and anti-HCV.