Fig. 5.

Examples from non-enema group showing TAC at 45 min, 2 and 4 h PET from tumour (a, c) and bladder (b, d). The TACs in a and b corresponds to patient 1 (P1) in Fig. 4 a–c and the TACs in c and d correspond to patient 2 (P2) in Fig. 4 d–f. The TACs show the effect of changes in bladder activity on apparent tumour activity at each time point. Although patient 2 emptied their bladder before the 2 h scan, the activity accumulated again at 4 h and consequently the activities in both bladder and tumour first dropped at 2 h (compared to 45 min) and then increased again at 4 h (compared to 2 h). This shows the effect of changes in bladder (and possibly non-tumour) activity on tumour TAC. TAC = time-activity curve; min = minutes; h = hour; PET = positron emission tomography; ml = millilitre; 1 millilitre = 1 cm³ kBq = kilo Becquerel