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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Menopause. 2017 Oct;24(10):1175–1184. doi: 10.1097/GME.0000000000000916

Figure 3.

Figure 3

The effects of sertraline on atherosclerosis in the individual territories of the carotid arteries in depressed and nondepressed monkeys. The data were analyzed by 2 (placebo, sertraline) X 2 (nondepressed, depressed) analyses of covariance (ANCOVAs) adjusting for baseline total plasma cholesterol/high-density lipoprotein cholesterol. A, Atherosclerosis extent in the right common carotid artery. There were no main effects of sertraline (p = 0.070) or depression (p = 0.410), but a significant interaction effect was observed (p=0.028). B, Atherosclerosis extent in the right carotid bifurcation. There were no main effects of sertraline (p = 0.428) or depression (p = 0.318), but a suggestive interaction effect was observed (p=0.057). C, Atherosclerosis extent in the right internal carotid artery. There were no effects of sertraline, depression, or their interaction (p’s all > 0.05). D, Atherosclerosis extent in the left carotid artery (LCC, LCB, and LIC). There were no effects of sertraline, depression, or their interaction (p’s all > 0.05). Adjusted means of the distributions of transformed data converted to original units are depicted in all graphs. LCC=left common carotid; LCB=left carotid bifurcation; LCC=left common carotid.