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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Mol Microbiol. 2017 Aug 4;106(1):74–92. doi: 10.1111/mmi.13754

Figure 8.

Figure 8

(A) Diagram of the known expression sites in T. brucei Lister 427 (according to (Hertz-Fowler et al., 2008, Cross et al., 2014, Kolev et al., 2012). Note that the distance from the closest promoter to the VSG start codon can range from 0.84 kb (top) to 56.6 kb (bottom). (B) Depiction of the difference in the number of Pol I complexes (black outline ovals) and spliced leader (SL) RNA molecules required to transcribe and process a primary transcript from a ‘minimalistic’ MES and a ‘full-length’ BES, assuming similar rates of VSG mRNA production.