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Single- and double-dose effects measured by relative risks (RRs) for minor alleles of 15 fetal single-nucleotide polymorphisms for the poled category of isolated cleft lip only (CLO) or isolated cleft lip and palate (CLP; first panel) and for nonisolated cleft lip only or nonisolated cleft lip and palate (second panel). Black squares represent single-dose effects; red squares represent double-dose effects; and lines are 95% confidence intervals.
