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. 2017 Sep 20;12(9):e0184993. doi: 10.1371/journal.pone.0184993

Table 1. Characteristics of the included studies.

Author, year Country Study design Size GA(w) BW(g) Ascertainment of exposure; outcome Risk of bias; quality
Tsimis 2016 [13] United States Retrospective cohort 374 case:26.3±2.2 control:28.0±2.5 case:868±237 control:993±276 Medical records; cranial ultrasound 6 weeks after birth No representativeness of the exposed cohort;NOS:8
Tawil 2012 [6] Kingdom of Saudi Arabia Case-control 118 case:27.4 control:26.2 case:1019.0 control:824.3 Medical records; cranial ultrasound at 1 week, 2 weeks and 5–6 weeks after birth No representativeness of the cases, no report of non-response rate;NOS:7
Resch 2012 [14] Austria Case-control 141 case:30.3±2.3(25–35) control:30.4±2.4(24–35) case:1450±550(618–2500) control:1446±358(685–2510) Medical records; cranial ultrasound at days 1, 3, and 5 of life and repeated weekly until diagnosis No representativeness of the cases, no report of non-response rate;NOS:7
Hatzidaki 2009 [12] Greece Case-control 135 case:30.1±2.6;control:30.4±2.4 case:1278.4±428.2 control:1375.5±378.6 Medical records; cranial ultrasound within 1 week after birth No representativeness of the cases, no report of non-response rate;NOS:7
Bauer 2009 [11] Austria Case-control 340 case:31.1±2.5 control:31.3±2.5 case:1278.4±428.2 control:1518±425 Medical records; cranial ultrasound within 7 weeks after birth No representativeness of the cases, no report of non-response rate;NOS:7
Oda 2008 [20] Japan Retrospective cohort 30 case:28.7±1.94 control:30.0±2.37 case:1410±402 control:1525±525 Medical records; cranial ultrasound before 72 hours and at 2 weeks after birth No representativeness of the exposed cohort, follow-up was not long enough for outcome;NOS:7
Silva 2006 [10] United States Case-control 352 case:27.3±2.7 control:27.4±2.7 case:958±306 control:1038±381 Medical records; cranial ultrasound No representativeness of the cases, no report of non-response rate;NOS:7
Murata 2005 [8] Japan Retrospective cohort 201 case:29.4±2.1 control:29.6±2.1 case:1324±324 control:1304±371 Medical records; cranial ultrasound within 4 weeks after birth No representativeness of the exposed cohort, follow-up was not long enough for outcome;NOS:7
Locatelli 2005 [21] Italy Retrospective cohort 196 case:28.6±2.6 control:30.3±2.5 case:1183±362 control:1502±489 Medical records; cranial ultrasound at days 1, 3, and 7 of life and repeated every 2 weeks until 40 postconceptional weeks No representativeness of the exposed cohort;NOS:8
Graham 2004 [9] United States Case-control 150 case:22.5±2.7 control:27.4±2.6 case:1053±402 control:966±285 Medical records; cranial ultrasound 6 weeks after birth No representativeness of the cases, no report of non-response rate;NOS:7
Pladys 2001 [22] France Retrospective cohort 46 case:29.4(27.4–31.3) control:29.3(27–31.7) case:1285(800–1945) control:1310(665–1980) Medical records; cranial ultrasound within 6–8 weeks after birth No representativeness of the exposed cohort, follow-up was not long enough for outcome;NOS:7
Kubota 2001 [7] Japan Case-control 51 29.8±2.7 case:1399±505 control:1410±479 Medical records; cranial ultrasound within 4 weeks after birth and once per week thereafter No representativeness of the cases, no report of non-response rate;NOS:7
Resch 2000 [23] Austria Case-control 3187 31±2.5(26–35) case:1511±456 control:1499±446 Medical records; cranial ultrasound at days 1, 3, and 5 of life and repeated weekly until diagnosis No representativeness of the cases, no report of non-response rate;NOS:7
Spinillo 1998 [24] Italy Retrospective cohort 349 case:29.4±2.2 control:30.5±2.5 case:1267±378 control:1452±445 Medical records; cranial ultrasound within 2 weeks after birth No representativeness of the exposed cohort;NOS:8
Perlman 1996 [25] United States Retrospective cohort 709 case:29.4±1.5 control:26.6±1.8 case:1285±301 control:904±248 Medical records; cranial ultrasound within 1 week after birth No representativeness of the exposed cohort;NOS:8

Abbreviations: GA (w), gestational age (weeks); BW (g), birth weight (grams); NOS, score of Newcastle-Ottawa scale.