Table 5. Comparison of patients without mMRC improvement and with mMRC improvement after bariatric surgery based on variations of clinical, respiratory and laboratory parameters in dyspneic patients before surgery according mMRC scale (n = 38).
| No mMRC improvement (n = 13) | mMRC improvement (n = 25) | p | ||
|---|---|---|---|---|
| Clinical parameters | ||||
| Δ weight (kg) | -26.1 (± 10.1) | -25.7 (± 13.6) | 0.78 | |
| Δ WM (cm) | -17 (± 11) | -16 (± 10) | 0.82 | |
| Δ HM (cm) | -14 (± 13) | -14 (± 9) | 0.88 | |
| Δ WM/HM | -0.03 (± 0.09) | -0.02 (± 0.08) | 0.61 | |
| Δ BMI (kg/m²) | -9.4 (± 3.5) | -9.3 (± 4.4) | 0.90 | |
| 6-minute walk test | ||||
| Δ 6MWT distance (m) | 33 (± 55) | 19 (± 53) | 0.34 | |
| Δ SpO2 at rest (%) | 0.7 (± 2.2) | 0.7 (± 1.4) | 0.45 | |
| Δ SpO2 after 6MWT (%) | 2.1 (± 3.6) | 0.7 (± 3.2) | 0.15 | |
| Arterial blood gases | ||||
| Δ PO2 (mmHg) | 12.2 (± 12.4) | 5.3 (± 21.9) | 0.57 | |
| Δ PCO2 (mmHg) | -1.8 (± 5.0) | -0.7 (± 5.4) | 0.97 | |
| Pulmonary function tests | ||||
| Δ VC (L) | 0.15 (± 0.42) | 0.06 (± 0.20) | 0.68 | |
| Δ VC (% pred) | 4 (± 13) | 7 (± 18) | 0.60 | |
| Δ FVC (L) | 0.12 (± 0.41) | 0.08 (± 0.30) | 0.98 | |
| Δ FVC (% pred) | 3 (± 13) | 2 (± 8) | 0.89 | |
| Δ FEV1 (L) | 0.07 (± 0.32) | 0.07 (± 0.20) | 0.86 | |
| Δ FEV1 (% pred) | 3 (± 11) | 4 (± 7) | 0.99 | |
| Δ IC (L) | -0.02 (± 0.41) | -0.44 (± 0.40)* | 0.01 | |
| Δ IC (% pred) | -1 (± 19) | -19 (± 17)* | 0.01 | |
| Δ ERV (L) | 0.17 (± 0.32) | 0.49 (± 0.35)* | 0.01 | |
| Δ ERV (% pred) | 17 (± 32) | 45 (± 31)* | 0.01 | |
| Δ RV (L) | 0.44 (± 0.36) | 0.01 (± 0.68) | 0.08 | |
| Δ RV (% pred) | 27 (± 26) | -1 (± 38) | 0.06 | |
| Δ TLC (L) | 0.48 (± 0.46) | -0.12 (± 0.77)* | 0.01 | |
| Δ TLC (% pred) | 10 (± 9) | -2 (± 15)* | 0.02 | |
| Δ DLCO (% pred) | 1 (± 13) | -7 (± 13) | 0.07 | |
| Laboratory parameters | ||||
| Δ CRP (mg/L) | -2.1 (± 3.2) | -7.2 (± 5.9)* | 0.01 | |
| Δ Haemoglobin (g/L) | 1 (± 12) | - 2 (± 8) | 0.67 | |
| Δ NT-pro BNP (pg/mL) | 11.8 (± 117.5) | 6.9 (± 41.2) | 0.72 | |
Data are expressed as mean ± SD.
Abbreviations: WM: Waist measurement; HM: Hip measurement; BMI: Body Mass Index; 6MWT: six-minute walk test; SpO2: Pulse Oxygen Saturation; PaO2: Partial arterial pressure of oxygen; PaCO2: Partial arterial pressure of carbon dioxide; VC: Vital capacity; FVC: Forced vital capacity; FEV1: Forced expiratory volume in one second; IC: Inspiratory capacity; ERV: Expiratory Reserve Volume; RV: Residual Volume; TLC: Total Lung Capacity; DLCO: Carbon Monoxide Diffusing Capacity of the Lung; CRP: C-reactive protein; NT-pro BNP: N-terminal prohormone of brain natriuretic peptide.
*p<0.05