Table 1. Number of SNPs by minor allele frequency bins, as well as the number and percentage of significant SNPs, using several definitions of statistical significance.
MAF bins | <0.001 | 0.001–0.005 | 0.005–0.01 | 0.01–0.05 | ≥0.05 | All |
---|---|---|---|---|---|---|
# SNPs | 0 | 0 | 240,423 | 2,500,103 | 6,715,230 | 9,455,778 |
(%) of row | 0 | 0 | 2.54 | 26.44 | 71.02 | 100 |
P deviated* | 0 | 0 | 103 | 1,988 | 30,417 | 32,508 |
(%) of row | 0 | 0 | 0.32 | 6.11 | 93.57 | 100 |
P<5x10-8 | 0 | 0 | 0 | 61 | 2,152 | 2,213 |
(%) of row | 0 | 0 | 0 | 2.76 | 97.24 | 100 |
P<1x10-8 | 0 | 0 | 0 | 39 | 1,836 | 1,875 |
(%) of row | 0 | 0 | 0 | 2.08 | 97.92 | 100 |
*P deviated: the p-value was in the tail of the QQ plot, after a point of inflexion where the line sloped away from the line of expectation. This includes all SNPs with p< 0.0074