. 2017 Sep 20;7:11991. doi: 10.1038/s41598-017-11819-4

Table 1.

Comparative fermentation data of the three-phase and two-phase fermentation strategies.

Clone/candidate	VAMAX1		VAMAX2
Fermentation strategy	3-phase	2-phase	3-phase	2-phase
Biomass yield on methanol [g g⁻¹]	0.18	0.28	0.19	0.27
Growth rate before induction [1 h⁻¹]	0.069	0.179	0.069	0.193
Growth rate during induction phase [1 h⁻¹]	0.007	0.030	0.007	0.031
Specific productivity [mg g⁻¹ h⁻¹]	0.011	0.019	0.007	0.019
Final product concentration [mg L⁻¹]	18 ± 1	28 ± 1	11 ± 1	27 ± 2
Total product yield (15-L scale) [mg]	297 ± 14	474 ± 17	186 ± 8	455 ± 28
Space-time yield (induction) [mg L⁻¹ h⁻¹]	0.623	0.519	0.381	0.524
Space-time yield (total process) [mg L⁻¹ h⁻¹]	0.224	0.343	0.136	0.343

Technical standard deviations (n = 3) are shown for the final product concentrations and total product yields.