Table 1.
HOTAIR expression and clinicopathological characteristics in RCC.
| Group | HOTAIR-Low N = 43 (%) | HOTAIR-High N = 21(%) | P-valuea |
|---|---|---|---|
| Age | 0.787 | ||
| ≥60 years | 29 (67) | 13 (61) | |
| <60 years | 14 (33) | 8 (39) | |
| Sex | 0.16 | ||
| Male | 27 (63) | 17 (81) | |
| Female | 16 (37) | 4 (19) | |
| Types of nephrectomy | 0.153 | ||
| Radical | 26 (60) | 17 (81) | |
| Partial | 17 (40) | 4 (19) | |
| Fuhrman’s nuclear grade | 0.0038 | ||
| Grades 1–2 | 40 (93) | 13 (61) | |
| Grades 3–4 | 3 (7) | 8 (39) | |
| Vascular invasion | 0.0138 | ||
| No | 31 (72) | 8 (39) | |
| Yes | 12 (28) | 13 (61) | |
| Tumor diameter | 0.057 | ||
| <4 cm | 19 (44) | 4 (19) | |
| ≥4 cm | 24 (56) | 17 (81) | |
| T stage | 0.068 | ||
| T1 + T2 | 35 (81) | 12 (57) | |
| T3 + T4 | 8 (19) | 9 (43) | |
| N stage | 0.0027 | ||
| N0 | 43 (100) | 16 (76) | |
| N1–2 | 0 (0) | 5 (24) | |
| M stage | 0.0135 | ||
| M0 | 39 (91) | 13 (61) | |
| M1 | 4 (9) | 8 (39) | |
| TNM stage | 0.0025 | ||
| Stage I-II | 32 (74) | 7 (33) | |
| Stage III-IV | 11 (26) | 14 (67) | |
aThe statistical significance of differences between two groups was estimated by Fisher’s exact test.