Table 1.
1H NMR data for compounds 1–6 in CDCl3 (δ in ppm, J in Hz).
| Pos. | 1b | 2b | 3a | 4 a | 5a | 6a |
|---|---|---|---|---|---|---|
| 2 | 6.66, s | 6.07, s | 6.17, s | 6.24, s | 6.60, s | 6.20, s |
| 3 | 3.15, m | 3.18, m | 3.17, m | 3.17, m | 3.17, m | 3.16, m |
| 4 | 2.58, m | 2.58, m | 2.62, m | 2.70, m | 2.59, m | 2.77, dd (2.4, 5.6) |
| 5 | 2.58, m | 2.61, m | 2.55, m | 2.56, m | 2.59, m | 2.56, m |
| 7 | 5.35, s | 5.37, brs | 5.37, brs | 5.44, brs | 5.45, brs | 5.43, brs |
| 8 | 3.00, d (10.8) | 3.05, d (10.2) | 2.97, brd (9.2) | 3.08, d (10.8) | 3.21, m | 3.06, d (10.4) |
| 10a | 1.15, m | 1.16, m | 1.18, m | 1.16, m | 1.17, m | 1.18, m |
| 10b | — | 1.30, m | — | — | — | — |
| 11 | 1.18, d (7.2) | 1.21, d (6.6) | 1.21, d (6.8) | 1.22, d (7.2) | 1.21, d (6.6) | 1.24, d (7.2) |
| 12 | 1.72, s | 1.75, s | 1.74, s | 1.76, s | 1.76, s | 1.77, s |
| 13 | 6.23, d (10.8) | 6.25, d (10.8) | 6.23, d (10.2) | 6.19, d (10.8) | 6.06, d (11.0) | 6.19, d (11.2) |
| 15a | 2.17, d (12.6) | 2.15, d (10.8) | 2.16, brd (11.4) | 1.98, m | 1.88, m | 1.95, m |
| 15b | 1.80, t (12.0, 24.0) | 1.80, t (12.0, 24.6) | 1.89, m | 1.87, m | 1.76, m | 1.85, m |
| 16 | 2.58, m | 2.59, m | 2.55, m | 1.87, m | 1.76, m | 1.85, m |
| 17a | 2.60, m | 2.56, m | 2.78, m | 1.98, m | 1.98, m | 1.95, m |
| 17b | 2.21, d (15.0) | 2.30, d (16.0) | 2.55, m | 1.87, m | 1.88, m | 1.85, m |
| 18 | — | — | 3.76, m | 3.60, m | 3.60, m | |
| 19a | 2.76, m | 5.01, dd (2.4, 10.8) | 4.57, brd (8.0) | 1.39, m | 3.09, m | 3.42, m |
| 19b | — | — | — | 1.87, m | — | — |
| 20a | 3.85, ddd (2.4, 11.4, 17.4) | 2.92, m | 4.16, dd (11.1, 17.4) | 3.60, m | 4.11, dd (2.2, 18.7) | 4.20, d (17.6) |
| 20b | 2.40, ddd (,2.4, 7.8, 17.4) | — | 2.55, m | 1.92, m | 1.93, m | 1.90, m |
| 22 | 1.58, m | 1.56, m | 1.54, m | 1.55, m | 1.58, m | 1.54, m |
| 23/24 | 0.90, d (6.6) | 0.90, d (6.6) | 0.91, d (6.0) | 0.89, d (6.8) | 0.90, d (6.6) | 0.90, d (6.8) |
| 25 | 1.36, s | 1.35, s | 1.43, s | 1.55, s | 1.53, s | 1.54, s |
| 26a | 3.58, dd (4.8, 10.8) | 3.61, dd (5.4, 10.8) | 3.66, m | 3.60, m | 3.55, m | 3.56, m |
| 26b | 3.41, dd (6.0, 9.6) | 3.45, dd (7.2, 10.8) | 3.53, t (7.3, 17.0) | 3.35, m | 3.33 t (9.2, 18.5) | 3.34, t (9.2, 18.4) |
| 27 | — | 3.34, s | — | — | 3.51, s | — |
aSpectra were recorded at 400 MHz. bSpectra were recorded at 600 MHz.