TABLE 1.

Analysis of the pathogenic potential (PP) of hvKP1 and hvKP1Δpeg-344 after pulmonary challenge with or without the element of time

Strain	Inoculum (CFU)	Ma	PPb	PP1/PP2c	PPTd	PPT1/PPT2e
hvKP1 (1)	3.0 × 103	0.570	12.4		2.34
hvKP1Δpeg-344 (2)	2.8 × 103	0.125	4.75	2.6	0.59	3.97
hvKP1	3.0 × 104	1.000	3.33		0.833
hvKP1Δpeg-344	2.8 × 104	0.375	0.85	3.9	0.122	6.83
hvKP1	3.0 × 105	0.86	0.24		0.046
hvKP1Δpeg-344	2.8 × 105	0.875	0.27	0.88	0.046	1.0
hvKP1	3.0 × 106	0.860	0.024		0.008
hvKP1Δpeg-344	2.8 × 106	0.875	0.027	0.88	0.005	1.6

^aM, mortality fraction.

^bPP was calculated as 1/inoculum × 10^M × 10,000.

^cPP1/PP2, PP of hvKP1/PP of hvKP1Δpeg-344.

^dPP_T, pathogenic potential incorporating the element of time (PP × 1/T, where T is the mean number of days to death).

^ePP_T1/PP_T2, PP_T of hvKP1/PP_T of hvKP1Δpeg-344.