Pulmonary inflammatory response to A. baumannii in caspase-11+/+ and caspase-11−/− mice. (A) Neutrophils in BALF from caspase-11+/+ and caspase-11−/− mice infected with 2 × 108
A. baumannii bacteria. (B) MPO activity in lung tissue of caspase-11+/+ and caspase-11−/− mice infected with 2 × 108
A. baumannii bacteria. (C to F) Levels of IL-1β, IL-6, TNF-α, and IL-1α in BALF from caspase-11+/+ and caspase-11−/− mice infected with 2 × 108
A. baumannii bacteria. *, P < 0.05 versus casp-11+/+; **, P < 0.01 versus casp-11+/+; ***, P < 0.001 versus casp-11+/+. casp-11, caspase-11; Uninf, uninfected. The data are expressed as means ± SD. Each group contained 5 mice.