Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Tpl2−/− mice have greater bacterial dissemination during peak infection. Wild-type and Tpl2−/− mice were gavaged with 2 × 109 CFU Citrobacter rodentium (ICC180). Mice were euthanized at 8 or 11 dpi. Livers and spleens were collected, assessed for lesions (A and B), and homogenized to measure the bacterial burden (C and D). Dashed lines, limit of detection. Data from two or more independent experiments per time point were pooled (n ≥ 4 mice). *, P < 0.05 by two-way ANOVA.
