TABLE 1.
Differentially expressed genes for enzymes that catalyze generation of reactive oxygen species in LEW versus BN ratsa
| Ensembl gene no. | Gene name | Fold change in expression (FDR) |
|||
|---|---|---|---|---|---|
| BNToxo/BNPBS | LEWToxo/LEWPBS | LEWToxo/BNToxo | LEWPBS/BNPBS | ||
| ENSRNOG00000029179 | Cyp2d3 | NSD | −2.19 (0.0001) | 464.43 (2.03E−49) | 1,072.80 (8.18E−67) |
| ENSRNOG00000029178 | Cyp2d5 | NSD | −1.82 (0.02) | 221.12 (3.62E−18) | 402.16 (5.07E−26) |
| ENSRNOG00000009620 | Cybrd1 | NSD | 1.80 (0.0008) | 3.64 (1.08E−11) | 1.70 (0.004) |
Abbreviations: Cyp, cytochrome P450 family; Cybrd, cytochrome b reductase; FDR, false-discovery rate; NSD, not significantly different (FDR, 0.05); BNToxo and LEWToxo, T. gondii-inoculated BN and LEW rats, respectively; BNPBS and LEWPBS, PBS-inoculated BN and LEW rats, respectively.