TABLE I. Antifungal, antibacterial and antimalarial activities of endophytic fungal extracts associated with the plant Vellozia gigantea .
| Fungal species | UFMGCBa | Yeastsb | Filamentous fungib | Bacteria | Actinobacteriab | Malariac | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
|
|
|
|
||||||||
| CA | CG | CK | CN | AF | SA | SA MRS | EC | PA | MI | PC(D6)d | ||
| Diaporthe miriciae | 9720 | 148.79 | 11.40 | 40.83 | > 200 | > 200 | > 200 | 65.80 | > 200 | > 200 | > 200 | 94 |
| Trichoderma effusum | 9736 | > 200 | > 200 | > 200 | > 200 | > 200 | > 200 | 64.60 | > 200 | > 200 | 31.98 | 24 |
| Penicillium herquei | 9829 | > 200 | > 200 | > 200 | > 200 | > 200 | 24.40 | 9.98 | > 200 | > 200 | > 200 | 17 |
| P. adametzii | 9894 | > 200 | > 200 | > 200 | > 200 | > 200 | > 200 | 23.24 | > 200 | > 200 | > 200 | 36 |
| P. quebecense | 9928 | 10.81 | 18.81 | 14.89 | > 200 | > 200 | > 200 | >200 | > 200 | > 200 | > 200 | 39 |
| Control drugs | Amphotericin B | 0.28 | 0.29 | 0.63 | 0.31 | 1.43 | - | - | - | - | - | - |
| Ciprofloxacin | - | - | - | - | - | 0.13 | 0.11 | 0.01 | 0.09 | 0.40 | - | |
| Chloroquine | - | - | - | - | - | - | - | - | - | - | 90 | |
| Artemisinin | - | - | - | - | - | - | - | - | - | - | 92 | |
a: culture of microorganisms and cells of the Universidade Federal of Minas Gerais; b: concentration which the extract displayed activity against yeasts, filamentous fungi, bacteria and actinobacteria; c: against Plasmodium falciparum the extract was assayed at 15.866 µg mL-1 and the results showed in (d) percentage of inhibition. CA: Candida albicans; CG: C. glabrata; CK: C. krusei; CN: Cryptococcus neformans; AF: Aspergillus fumigatus; SA: Staphylococcus aureus; SA MRS: S. aureus methicillin resistant; EC: Escherichia coli; PA: Pseudomonoas aeruginosa; MI: Mycobacterium intracellulare; PC (D6) P. falciparum chloroquine sensitive.