Table 2.
Cortical thickness | V1 Mean [95% CIa] | V2 Mean [95% CIa] | V3 Mean [95% CIb] | MCV (%) [95% CI] | MRD (%) [95% CI] | ICC | Rating 3%c | Rating 10%c |
---|---|---|---|---|---|---|---|---|
Whole‐brain GM |
2.67 [2.62, 2.71] |
2.66 [2.62, 2.70] |
2.67 [2.62, 2.71 |
0.80 [0.61, 0.98] |
1.1 [0.80, 1.3] |
0.980 |
N = 3 (High) |
N = 2 (High) |
Left brain segments | ||||||||
lh mean thickness |
2.67 [2.62, 2.72] |
2.66 [2.62, 2.70] |
2.67 [2.62, 2.71] |
0.88 [0.64, 1.0] |
1.2 [0.92, 1.4] |
0.979 |
N = 3 (High) |
N = 2 (High) |
lh bankssts |
2.64 [2.57, 2.71] |
2.64 [2.59, 2.70] |
2.64 [2.57, 2.70] |
2.1 [1.6, 2.5] |
2.7 [2.1, 3.2] |
0.940 |
N = 11 (High) |
N = 2 (High) |
lh caudal anterior cingulate |
2.77 [2.68, 2.86] |
2.73 [2.63, 2.83] |
2.74 [2.63, 2.84] |
2.6 [1.9, 3.2] |
3.3 [2.5, 4.1] |
0.959 |
N = 17 (High) |
N = 3 (High) |
lh caudal middle frontal |
2.74 [2.68, 2.79] |
2.72 [2.67, 2.77] |
2.71 [2.66, 2.77] |
1.3 [1.0, 1.7] |
1.7 [1.3, 2.1] |
0.957 |
N = 5 (High) |
N = 2 (High) |
lh cuneus |
1.99 [1.92, 2.06] |
2.03 [1.96, 2.10] |
2.02 [1.95, 2.09] |
2.4 [1.7, 3.1] |
3.2 [2.2, 4.2] |
0.962 |
N = 13 (High) |
N = 3 (High) |
lh entorhinal |
3.59 [3.49, 3.70] |
3.51 [3.41, 3.62] |
3.56 [3.46, 3.65] |
3.9 [3.0, 4.8] |
5.0 [3.9, 6.1] |
0.747 |
N = 42 (Low) |
N = 5 (High) |
lh fusiform |
2.88 [2.83, 2.94] |
2.87 [2.81, 2.93] |
2.87 [2.81, 2.93] |
1.3 [1.0, 1.5] |
1.6 [1.3, 1.9] |
0.889 |
N = 5 (High) |
N = 2 (High) |
lh inferior parietal |
2.63 [2.57, 2.68] |
2.63 [2.58, 2.67] |
2.64 [2.58, 2.70] |
1.1 [0.85, 1.4] |
1.5 [1.1, 1.8] |
0.977 |
N = 4 (High) |
N = 2 (High) |
lh inferior temporal |
3.01 [2.94, 3.07] |
3.01 [2.95, 3.07] |
3.01 [2.95, 3.08] |
1.4 [1.1, 1.7] |
1.8 [1.5, 2.2] |
0.967 |
N = 6 (High) |
N = 2 (High) |
lh isthmus cingulate |
2.54 [2.46, 2.61] |
2.54 [2.46, 2.62] |
2.51 [2.43, 2.60] |
2.4 [2.0, 2.9] |
3.1 [2.6, 3.7] |
0.950 |
N = 15 (High) |
N = 3 (High) |
lh lateral occipital |
2.28 [2.22, 2.33] |
2.28 [2.22, 2.34] |
2.30 [2.24, 2.36] |
1.6 [1.1, 2.0] |
2.1 [1.5, 2.7] |
0.966 |
N = 7 (High) |
N = 2 (High) |
lh lateral orbitofrontal |
2.92 [2.85, 2.98] |
2.90 [2.83, 2.96] |
2.87 [2.80, 2.95] |
1.9 [1.5, 2.3] |
2.4 [1.7, 3.0] |
0.955 |
N = 9 (High) |
N = 2 (High) |
lh lingual |
2.21 [2.15, 2.27] |
2.21 [2.15, 2.27] |
2.21 [2.15, 2.28] |
1.8 [1.3, 2.3] |
2.3 [1.7, 3.0] |
0.974 |
N = 8 (High) |
N = 2 (High) |
lh medial orbitofrontal |
2.72 [2.65, 2.79] |
2.70 [2.63, 2.76] |
2.68 [2.61, 2.75] |
3.0 [2.5, 3.5] |
3.9 [3.3, 4.5] |
0.898 |
N = 21 (Moderate) |
N = 3 (High) |
lh middle temporal |
3.10 [3.03, 3.17] |
3.08 [3.01, 3.14] |
3.10 [3.03, 3.16] |
1.1 [0.78, 1.4] |
1.4 [1.0, 1.8] |
0.977 |
N = 4 (High) |
N = 2 (High) |
lh parahippocampal |
2.83 [2.70, 2.96] |
2.80 [2.67, 2.93] |
2.80 [2.66, 2.93] |
2.2 [1.9, 2.5] |
2.8 [2.4, 3.3] |
0.984 |
N = 13 (High) |
N = 3 (High) |
lh paracentral |
2.53 [2.48, 2.59] |
2.54 [2.49, 2.59] |
2.56 [2.50, 2.62] |
1.4 [1.1, 1.8] |
1.8 [1.4, 2.2] |
0.964 |
N = 6 (High) |
N = 2 (High) |
lh parsopercularis |
2.85 [2.80, 2.91] |
2.85 [2.80, 2.90] |
2.85 [2.78, 2.91] |
0.97 [0.74, 1.2] |
1.3 [0.97, 1.5] |
0.980 |
N = 3 (High) |
N = 2 (High) |
lh parsorbitalis |
3.01 [2.94, 3.07] |
2.98 [2.92, 3.04] |
3.04 [2.97, 3.11] |
1.8 [1.3, 2.4] |
2.3 [1.6, 3.1] |
0.963 |
N = 8 (High) |
N = 2 (High) |
lh parstriangularis |
2.73 [2.67, 2.80] |
2.71 [2.65, 2.77] |
2.71 [2.64, 2.78] |
1.3 [1.0, 1.6] |
1.6 [1.3, 2.0] |
0.981 |
N = 5 (High) |
N = 2 (High) |
lh pericalcarine |
1.76 [1.69, 1.83] |
1.80 [1.72, 1.88] |
1.79 [1.72, 1.86] |
2.7 [2.0, 3.4] |
3.5 [2.6, 4.4] |
0.978 |
N = 17 (High) |
N = 3 (High) |
lh postcentral |
2.20 [2.15, 2.25] |
2.20 [2.16, 2.25] |
2.20 [2.15, 2.25] |
1.2 [0.90, 1.5] |
1.6 [1.2, 2.0] |
0.972 |
N = 5 (High) |
N = 2 (High) |
lh posterior cingulate |
2.60 [2.54, 2.65] |
2.60 [2.54, 2.65] |
2.58 [2.52, 2.64] |
1.4 [1.1, 1.7] |
1.9 [1.4, 2.3] |
0.957 |
N = 6 (High) |
N = 2 (High) |
lh precentral |
2.73 [2.69, 2.77] |
2.72 [2.68, 2.75] |
2.73 [2.69, 2.77] |
1.0 [0.73, 1.3] |
1.3 [0.96, 1.6] |
0.951 |
N = 4 (High) |
N = 2 (High) |
lh precuneus |
2.55 [2.49, 2.60] |
2.54 [2.49, 2.60] |
2.55 [2.50, 2.61] |
0.98 [0.75, 1.2] |
1.3 [0.97, 1.6] |
0.983 |
N = 4 (High) |
N = 2 (High) |
lh rostral anterior cingulate |
3.06 [2.95, 3.17] |
3.02 [2.89, 3.15] |
3.02 [2.89, 3.15] |
3.0 [2.2, 3.9] |
3.9 [2.8, 5.0] |
0.952 |
N = 21 (Moderate) |
N = 3 (High) |
lh rostral middle frontal |
2.62 [2.56, 2.69] |
2.60 [2.54, 2.65] |
2.59 [2.52, 2.66] |
1.5 [1.2, 1.9] |
2.0 [1.6, 2.4] |
0.971 |
N = 6 (High) |
N = 2 (High) |
lh superior frontal |
2.86 [2.81, 2.91] |
2.84 [2.79, 2.88] |
2.86 [2.82, 2.91] |
1.6 [1.1, 2.1] |
2.0 [1.4, 2.7] |
0.918 |
N = 7 (High) |
N = 2 (High) |
lh superior parietal |
2.30 [2.24, 2.35] |
2.31 [2.26, 2.35] |
2.31 [2.26, 2.36] |
1.1 [0.84, 1.4] |
1.4 [1.1, 1.7] |
0.980 |
N = 4 (High) |
N = 2 (High) |
lh superior temporal |
3.05 [2.99, 3.11] |
3.05 [2.99, 3.11] |
3.07 [3.00, 3.14] |
1.2 [0.87, 1.5] |
1.5 [1.1, 1.9] |
0.970 |
N = 4 (High) |
N = 2 (High) |
lh supramarginal |
2.75 [2.69, 2.81] |
2.75 [2.70, 2.81] |
2.75 [2.69, 2.82] |
1.0 [0.83, 1.2] |
1.3 [1.1, 1.6] |
0.983 |
N = 4 (High) |
N = 2 (High) |
lh frontal pole |
3.10 [2.99, 3.21] |
3.12 [3.01, 3.24] |
3.13 [3.01, 3.25] |
3.2 [2.1, 4.3] |
4.3 [2.8, 5.8] |
0.918 |
N = 23 (Moderate) |
N = 3 (High) |
lh temporal pole |
3.97 [3.88, 4.06] |
3.97 [3.89, 4.06] |
3.91 [3.81, 4.02] |
2.2 [1.7, 2.8] |
2.9 [2.2, 3.6] |
0.919 |
N = 12 (High) |
N = 2 (High) |
lh transverse temporal |
2.67 [2.57, 2.78] |
2.70 [2.60, 2.79] |
2.69 [2.60, 2.79] |
2.0 [1.5, 2.6] |
2.6 [2.0, 3.3] |
0.971 |
N = 11 (High) |
N = 2 (High) |
lh insula |
3.22 [3.15, 3.28] |
3.24 [3.18, 3.30] |
3.23 [3.17, 3.29] |
2.2 [1.6, 2.8] |
2.9 [2.1, 3.7] |
0.890 |
N = 12 (High) |
N = 2 (High) |
Right brain segments | ||||||||
rh mean thickness |
2.67 [2.62, 2.71] |
2.66 [2.62, 2.70] |
2.66 [2.62, 2.71] |
0.83 [0.64, 1.0] |
1.1 [0.84, 1.4] |
0.978 |
N = 3 (High) |
N = 2 (High) |
rh bankssts |
2.81 [2.75, 2.87] |
2.0 [2.75, 2.86] |
2.76 [2.70, 2.82] |
1.4 [1.2, 1.7] |
1.9 [1.5, 2.2] |
0.967 |
N = 6 (High) |
N = 2 (High) |
rh caudal anterior cingulate |
2.66 [2.58, 2.74] |
2.65 [2.59, 2.72] |
2.67 [2.58, 2.75] |
2.3 [1.9, 2.7] |
3.0 [2.4, 3.5] |
0.948 |
N = 14 (High) |
N = 3 (High) |
rh caudal middle frontal |
2.65 [2.60, 2.70] |
2.65 [2.60, 2.70] |
2.64 [2.59, 2.69] |
1.3 [0.99, 1.6] |
1.7 [1.3, 2.1] |
0.958 |
N = 5 (High) |
N = 2 (High) |
rh cuneus |
2.03 [1.96, 2.09] |
2.05 [1.98, 2.12] |
2.03 [1.96, 2.11] |
2.1 [1.4, 2.9] |
2.7 [1.9, 3.6] |
0.960 |
N = 11 (High) |
N = 2 (High) |
rh entorhinal |
3.61 [3.52, 3.70] |
3.56 [3.46, 3.66] |
3.66 [3.55, 3.78] |
4.2 [3.3, 5.1] |
5.6 [4.3, 6.8] |
0.781 |
N = 42 (Low) |
N = 5 (High) |
rh fusiform |
2.89 [2.84, 2.94] |
2.88 [2.83, 2.93] |
2.86 [2.81, 2.92] |
1.4 [1.1, 1.8] |
1.8 [1.4, 2.3] |
0.961 |
N = 6 (High) |
N = 2 (High) |
rh inferior parietal |
2.66 [2.59, 2.72] |
2.65 [2.60, 2.71] |
2.66 [2.60, 2.73] |
1.2 [0.95, 1.4] |
1.5 [1.2, 1.8] |
0.978 |
N = 5 (High) |
N = 2 (High) |
rh inferior temporal |
3.04 [2.99, 3.10] |
3.04 [2.97, 3.10] |
3.03 [2.96, 3.10] |
1.5 [1.1, 1.9] |
1.9 [1.4, 2.4] |
0.963 |
N = 6 (High) |
N = 2 (High) |
rh isthmus cingulate |
2.44 [2.40, 2.49] |
2.46 [2.40, 2.52] |
2.45 [2.39, 2.51] |
2.1 [1.6, 2.5] |
2.7 [2.0, 3.3] |
0.931 |
N = 11 (High) |
N = 2 (High) |
rh lateral occipital |
2.31 [2.25, 2.38] |
2.31 [2.25, 2.38] |
2.33 [2.26, 2.40] |
1.7 [1.3, 2.1] |
2.2 [1.6, 2.8] |
0.976 |
N = 8 (High) |
N = 2 (High) |
rh lateral orbitofrontal |
2.88 [2.82, 2.94] |
2.88 [2.83, 2.92] |
2.85 [2.79, 2.92] |
2.0 [1.6, 2.5] |
2.6 [2.1, 3.2] |
0.901 |
N = 11 (High) |
N = 2 (High) |
rh lingual |
2.29 [2.24, 2.35] |
2.31 [2.25, 2.38] |
2.31 [2.25, 2.37] |
1.6 [1.2, 2.0] |
2.1 [1.6, 2.6] |
0.977 |
N = 7 (High) |
N = 2 (High) |
rh medial orbitofrontal |
2.77 [2.72, 2.83] |
2.76 [2.69, 2.82] |
2.73 [2.67, 2.79] |
2.0 [1.5, 2.6] |
2.6 [1.9, 3.3] |
0.882 |
N = 12 (High) |
N = 2 (High) |
rh middle temporal |
3.17 [3.11, 3.23] |
3.15 [3.09, 3.21] |
3.14 [3.07, 3.21] |
1.3 [1.1, 1.6] |
1.7 [1.4, 2.1] |
0.972 |
N = 5 (High) |
N = 2 (High) |
rh parahippocampal |
2.78 [2.67, 2.89] |
2.76 [2.63, 2.89] |
2.76 [2.63, 2.88] |
2.2 [1.1, 2.8] |
2.8 [2.1, 3.5] |
0.980 |
N = 12 (High) |
N = 2 (High) |
rh paracentral |
2.56 [2.50, 2.61] |
2.57 [2.51, 2.62] |
2.57 [2.51, 2.62] |
1.4 [1.2, 1.7] |
1.9 [1.5, 2.2] |
0.961 |
N = 6 (High) |
N = 2 (High) |
rh parsopercularis |
2.80 [2.75, 2.85] |
2.80 [2.75, 2.85] |
2.79 [2.74, 2.84] |
1.0 [0.76, 1.3] |
1.3 [0.97, 1.7] |
0.971 |
N = 4 (High) |
N = 2 (High) |
rh parsorbitalis |
3.02 [2.94, 3.10] |
3.03 [2.97, 3.08] |
3.02 [2.95, 3.08] |
1.8 [1.3, 2.3] |
2.4 [1.7, 3.0] |
0.953 |
N = 9 (High) |
N = 2 (High) |
rh parstriangularis |
2.73 [2.66, 2.80] |
2.72 [2.65, 2.78] |
2.71 [2.64, 2.78] |
1.5 [1.2, 1.8] |
2.0 [1.6, 2.4] |
0.970 |
N = 6 (High) |
N = 2 (High) |
rh pericalcarine |
1.77 [1.70, 1.84] |
1.80 [1.72, 1.89] |
1.79 [1.71, 1.86] |
2.8 [2.2, 3.4] |
3.7 [2.9, 4.5] |
0.967 |
N = 18 (High) |
N = 3 (High) |
rh postcentral |
2.17 [2.12, 2.22] |
2.19 [2.13, 2.24] |
2.16 [2.10, 2.21] |
1.5 [0.81, 2.2] |
1.9 [1.1, 2.7] |
0.929 |
N = 7 (High) |
N = 2 (High) |
rh posterior cingulate |
2.62 [2.55, 2.68] |
2.61 [2.54, 2.68] |
2.60 [2.55, 2.66] |
1.3 [0.87, 1.7] |
1.7 [1.2, 2.2] |
0.962 |
N = 5 (High) |
N = 2 (High) |
rh precentral |
2.69 [2.65, 2.73] |
2.67 [2.63, 2.71] |
2.68 [2.64, 2.72] |
1.2 [0.70, 1.6] |
1.5 [0.691, 2.0] |
0.929 |
N = 4 (High) |
N = 2 (High) |
rh precuneus |
2.54 [2.48, 2.59] |
2.54 [2.48, 2.59] |
2.54 [2.48, 2.60] |
1.0 [0.78, 1.1] |
1.3 [1.0, 1.5] |
0.985 |
N = 4 (High) |
N = 2 (High) |
rh rostral anterior cingulate |
3.12 [3.03, 3.21] |
3.09 [3.00, 3.18] |
3.09 [3.00, 3.19] |
3.1 [2.3, 3.8] |
3.9 [2.9, 4.8] |
0.899 |
N = 23 (Moderate) |
N = 3 (High) |
rh rostral middle frontal | 2.56 [2.52, 2.60] |
2.56 [2.51, 2.60] |
1.4 [1.1, 1.7] |
1.8 [1.4, 2.2] |
0.952 |
N = 5 (High) |
N = 2 (High) |
|
rh superior frontal |
2.84 [2.78, 2.91] |
2.82 [2.77, 2.87] |
2.84 [2.78, 2.89] |
1.7 [1.3, 2.1] |
2.2 [1.7, 2.8] |
0.937 |
N = 8 (High) |
N = 2 (High) |
rh superior parietal |
2.32 [2.26, 2.37] |
2.32 [2.27, 2.37] |
2.32 [2.26, 2.37] |
1.1 [0.92, 1.4] |
1.5 [1.2, 1.8] |
0.987 |
N = 4 (High) |
N = 2 (High) |
rh superior temporal |
3.08 [3.01, 3.14] |
3.07 [2.95, 3.19] |
3.09 [3.02, 3.15] |
1.1 [0.73, 1.4] |
1.4 [0.95, 1.9] |
0.980 |
N = 4 (High) |
N = 2 (High) |
rh supramarginal |
2.74 [2.68, 2.80] |
2.73 [2.68, 2.78] |
2.72 [2.66, 2.79] |
1.1 [0.83, 1.4] |
1.4 [1.1, 1.8] |
0.981 |
N = 4 (High) |
N = 2 (High) |
rh frontal pole |
3.12 [2.99, 3.25] |
3.07 [2.95, 3.19] |
3.09 [2.96, 3.21] |
3.2 [2.2, 4.1] |
4.1 [2.8, 5.3] |
0.940 |
N = 24 (Moderate) |
N = 3 (High) |
rh temporal pole |
4.06 [3.96, 4.16] |
4.01 [3.91, 4.11] |
4.04 [3.93, 4.15] |
2.3 [1.8, 2.9] |
3.0 [2.3, 3.8] |
0.921 |
N = 14 (High) |
N = 3 (High) |
rh transverse temporal |
2.70 [2.61, 2.79] |
2.71 [2.60, 2.81] |
2.69 [2.59, 2.79] |
2.3 [1.6, 3.0] |
2.9 [2.1, 3.7] |
0.969 |
N = 13 (High) |
N = 3 (High) |
rh insula |
3.20 [3.14, 3.25] |
3.15 [3.10, 3.20] |
3.19 [3.13, 3.26] |
2.4 [1.8, 2.9] |
3.1 [2.4, 3.8] |
0.809 |
N = 14 (High) |
N = 3 (High) |
CI, confidence interval [lower limit, upper limit]; MCV, mean coefficient of variation; ICC, intraclass correlation; MRD, mean relative difference; lh, left hemisphere; rh, right hemisphere; GM, gray matter.
N = 25.
N = 22.
Reproducibility rating for 10% detection, power = 0.9, and significance = 0.05.