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. 2017 Aug 13;7(9):e00795. doi: 10.1002/brb3.795

Figure 2.

Figure 2

Mice lacking STXBP5/tomosyn‐1 kindle faster than wild‐type mice. (a) The average number stimulations (once per day) required to obtain a stage 5 seizure on 2 consecutive days. Data are presented as mean ± SEM; n = 14 for Tom+/+ mice and n = 15 for Tom−/− mice [U = 31, *p = .0028, Mann–Whitney U test). (b) The average current required to produce an AD for Tom+/+ versus Tom−/− mice (U = 81, p = .67, Mann–Whitney U test). (c) Time course to cumulatively reach a Racine stage 5 seizure (1 stimulation per day) for Tom+/+ (grey line, n = 14) and Tom−/− (black line, n = 15) mice. Note the 50% line corresponds to the average number of stimulations seen for each genotype in (a)