Table 2.
Lists of important virulence proteins of Yersinia ruckeri
| Protein | Function | Cascade of SVMs and PSI-BLAST, score |
|---|---|---|
| Gene expression modulator/haemolysin expression modulating protein | Haemolysin expression | 1.0520 |
| HtrA protease | Serine-type endopeptidase activity | 0.5097 |
| Outer membrane stress sensor protease DegQ serine protease | Serine-type endopeptidase activity | 1.0012 |
| Anti-sigma regulatory factor | Protein serine/threonine kinase activity | 0.9363 |
| Beta-barrel assembly-enhancing protease | Chaperone and a metalloprotease | 1.0339 |
| BarA-associated response regulator UvrY | Regulation of transcription | 0.9837 |
| Peptidyl-prolyl cis–trans isomerase | Protein folding | 0.9128 |
| PhoP family transcriptional regulator | Regulation of transcription | 1.0898 |
| LuxR family transcriptional regulator | Regulation of transcription | 1.0031 |
| AsnC family transcriptional regulator | Regulation of transcription | 0.7053 |
| RNA-binding protein Hfq | Regulation of transcription | 1.0260 |
| Anti-sigma factor antagonist | Regulation of transcription | 0.9804 |
| Attachment invasion locus protein | Invasion | 1.0123 |
| Invasin | Cell adhesion | 1.0130 |
| Superoxide dismutase Cu–Zn | Superoxide dismutase activity | 1.0003 |
| Molybdenum ABC transporter periplasmic molybdenum-binding protein ModA | Transporter activity | 0.8399 |
| DcrB protein | Required for phage C1 adsorption | 1.0009 |
| Methyl-accepting chemotaxis protein I | Chemotaxis | 0.9279 |
| Methyl-accepting chemotaxis protein III | Chemotaxis | 0.9922 |
Proteins were predicted by a method based on bi-layer cascade support vector machine using VirulentPred.