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IC50 values against docetaxel or gefitinib of docetaxel-resistant cell lines, with or without elacridar treatment.
| Docetaxel (nM) | Gefitinib (µM) | |||
|---|---|---|---|---|
| Elacridar (0.25 µg/ml) | − | + | − | + |
| H1299DR | 272.1 | 9.4 | >10 | >10 |
| HCC827DR | >1000 | 21.9 | 5.0 | 1.6 |
| HCC4006DR | >1000 | 0.3 | 8.3 | 4.7 |
