Figure 2.

C. albicans clinical isolates have differing biofilm architectures. (a) The biofilm-forming capacity of isolates was estimated by an XTT metabolic assay after 24 h of biofilm growth. Statistical significance was analyzed by ANOVA with pairwise comparison by the Holm–Sidak method, * p < 0.05, n = 3, representative data with SD shown; (b) Biofilms were imaged by scanning electron microscopy to visualize the surface architecture. Measurement bars represent 10 µm for 2000× images; (c) The depth of the biofilms was examined by cross-sectional analysis of C. albicans biofilms growing in microfluidic devices. Original images were taken at 10×.