Table 1.

Case Reports of Breastfed Infants Who Had Vitamin D Toxicity.

Year	Case Description	Diet and Vitamin Supplement	Laboratory Values/Treatment
20155	5.5 mo male—parental concerns of vitamin D overdosing, baby was fussy and constipated	Vitamin D3 400 IU/drop Dose the child received: 14 400 IU daily × 4 months (mom administered a dropper full or 1 mL)	25(OH)D >150 ng/mL (30-100) Outpatient treatment: discontinuation of vitamin D supplementation
20156	4 mo female—failure to thrive, dehydration; 3-day history of emesis, diarrhea, lethargy, dehydration	Exclusive breastfeeding Over-the-counter vitamin D3 Brand: Seeking Health, Liquid Vitamin D3 2000 IU/drop Dose the child received: 50 000 IU daily × 2 months (mom administered a dropper full)	25(OH)D 294 ng/mL (30-100) 1,25(OH)2D 138 pg/mL (22-84) Ca 18.7 mg/dL (9-11) Parathyroid hormone <6 pg/mL (15-65) Inpatient treatment: fluids, calcitonin, and bisphosphonates
20147	1.5 mo female—normal physical findings	Exclusive breastfeeding Vitamin D3 (Vigantol oil Merck KGaA) 10 drops daily, total of 200 000 IU per month	25(OH)D3 >400 nmol/L (50-125) Ca 2.72 mmol/L (2.2-2.7) Parathyroid hormone 6.6 pg/mL (10-69) Inpatient treatment: fluids, prednisolone, phenobarbital, and furosemide
20138	3 mo male—asymptomatic, parental concerns of vitamin D overdosing, slightly increased patellar deep tendon reflexes on examination	Exclusive breastfeeding Over-the-counter vitamin D3 Vitamin D preparation from a free-standing vitamin store 400 IU/drop Dose: 12 000 IU daily × 20 days (mom had given 1 mL)	25(OH)D3 422 ng/mL (30-100) 1,25(OH)2D 61 pg/mL (27-71) Ca 10.5 mg/dL (8.8-10.8) Parathyroid hormone <3 pg/mL (15-65) Outpatient treatment: discontinuation of vitamin D supplementation