Table 2.

Clinical Features.

Age and Sex	Signs and Symptoms	Vitamin D Supplement	Laboratory Values
3.5-month-old female	● Decreased feeding, lethargy, inconsolable crying for 1.5 weeks. ● 1-lb weight loss over 2 weeks ● Physical examination: pallor, dry lips, sunken fontanelles, sunken eyeballs, and hypertension	Whole Foods vitamin D3 2000 IU/mL, 1 mL daily for 2.5 months	● Serum Ca 21 mg/dL (8.8-11.2) ● 25(OH)D 644 ng/mL ● Parathyroid hormone <1 pg/mL (14-72)
2.5-month-old male	● decreased feeding, lethargy, inconsolable crying, vomiting after feeding for 2 days. ● physical examination: dry lips and sunken fontanelles	Emulsi-D3 (prescribed by chiropractor) vitamin D3 2000 IU per drop, given 1 mL instead of 1 drop—about 20 000 IU daily for 1.5 weeks	● Serum Ca 15 mg/dL (8.5-10.1) ● Ionized calcium 1.93 mmol/L (1.2-1.48) ● 25(OH)D 680 ng/mL ● 1,25(OH)2D 166 pg/mL (15-75) ● Parathyroid hormone <7 pg/mL (15-65)