Table 2.
Calculated parameters of fresh whole blood (450 ml donor blood with 63 ml anticoagulant) compared to component therapy with 1 packed red blood cells unit (hematocrit of 55% in 335 mL), 1 fresh frozen plasma unit (80% coagulation factor activity, 250 mL), and 1 platelet unit (5.5 × 1010 platelets in 50 mL).
| Fresh whole blood | 1:1:1 component therapy | |
|---|---|---|
| Dilution factor | 12% | 35% |
| Hematocrit | 33–43% | 29% |
| Clotting factor activity | 86% | 65% |
| Platelets | 130–350 × 109/L | 88 × 109/L |
| Fibrinogen content | 675–1800 mg | 400–500 mg |
| Bags of product (donor exposure) | 1 | 3–4 |