Table 1.
Clinical and demographic characteristics of Patients at the initial visit
| Clinical Variables | Diagnosis | |||||
|---|---|---|---|---|---|---|
| PD, n = 2352 | MSA, n = 130 | CBD, n = 69 | DLB, n = 60 | PSP, n = 102 | P | |
| Age: Mean ± SD, y | 67.0 ± 9.9 | 70.8 ± 8.8 | 68.3 ± 8.3 | 71.0 ± 7.5 | 70.0 ± 8.0 | <0.001 |
| Gender: No. (%) | ||||||
| Male | 1532 (65.1) | 89 (68.5) | 31 (44.9) | 41 (68.3) | 46 (45.1) | <0.001 |
| Female | 820 (34.9) | 41 (31.5) | 38 (55.1) | 19 (31.7) | 56 (54.9) | |
| Duration of symptoms: Mean ± SD, ya | 7.2 ± 6.7 | 5.4 ± 4.2 | 4.1 ± 3.2 | 5.0 ± 7.0 | 3.5 ± 2.7 | <0.001 |
| H&Y score: Mean ± SDb | 2.5 ± 0.7 | 3.1 ± 0.9 | 3.3 ± 1.2 | 3.3 ± 0.5 | 3.4 ± 1.0 | <0.001 |
| UPDRS III total: Mean ± SDc | 28.5 ± 11.7 | 38.0 ± 13.6 | 42.3 ± 16.7 | 37.1 ± 11.4 | 41.6 ± 13.6 | <0.001 |
| BDI: Mean ± SD | 10.4 ± 7.4 | 12.6 ± 7.5 | 13.4 ± 8.4 | 16.2 ± 8.8 | 13.7 ± 7.6 | <0.001 |
| Apathy scale: Mean ± SDd | 12.1 ± 6.5 | 16.4 ± 8.1 | 14.4 ± 7.3 | 19.6 ± 7.2 | 17.1 ± 8.2 | <0.001 |
Available in only 1949 patients with PD, 96 with MSA, 47 with CBD, 43 with DLB, and 70 with PSP.
Available in only 905 patients with PD, 54 with MSA, 17 with CBD, 14 with DLB, and 36 with PSP.
Available in only 1041 patients with PD, 59 with MSA, 21 with CBD, 17 with DLB, 41 with PSP.
Available in only 1204 patients with PD, 55 with MSA, 32 with CBD, 30 with DLB, 50 with PSP.
PD, Parkinson's disease; MSA, multiple system atrophy; CBD, corticobasal degeneration; DLB, dementia with Lewy bodies; PSP, progressive supranuclear palsy; SD, standard deviation; H&Y, Hoehn & Yahr clinical rating scale; UPDRS III, Unified Parkinson's Disease Rating Scale, part 3 (motor part); BDI, Beck Depression Inventory.