Table 4.

Preparation of difluoromethyl sulfones 47–50 and deuterodifluoromethyl sulfones 51–54.

Entry	Substrate	Conditions	Major Product	Yielda	% Db
1	43	Et3N, H2O		87%	na
2	44	Et3N, H2O		quant.	na
3	45	Et3N, H2O		89%	na
4	46	Et3N, H2O		85%	na
5	43	Et3N, D2O		74%	97%
6	44	Et3N, D2O		96%	96%
7	45	Et3N, D2O		80%	98%
8	46	Et3N, D2O		91%	98%

^aIsolated yields.

^bPercent deuterium incorporation were determined by ¹⁹F NMR, see Supporting Information for details.