Table 1. Phenotypes of Pdgfra CKO embryos of different Tm groups.
Tm | No. of embryo (n) | Mutant (n) | Cleft face | Short snout | Cranium defect | Cleft palate | Omphalocele | Spina bifida |
---|---|---|---|---|---|---|---|---|
E9.5 | 180 | 48 | 11 (23%) | 26 (54%) | 37 (77%) | 11 (23%) | 48 (100%) | 31 (65%) |
E10.5 | 45 | 12 | 0 (0%) | 1 (8%) | 1 (8%) | 0 (0%) | 12 (100%) | 2 (17%) |
E11.5 | 23 | 5 | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 5 (100%) | 0 (0%) |
E13.5 | 10 | 3 | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
% of the CKO embryos showing the respective anomaly was shown in parenthesis