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. 2017 Sep 21;12(9):e0184473. doi: 10.1371/journal.pone.0184473

Table 1. Phenotypes of Pdgfra CKO embryos of different Tm groups.

Tm No. of embryo (n) Mutant (n) Cleft face Short snout Cranium defect Cleft palate Omphalocele Spina bifida
E9.5 180 48 11 (23%) 26 (54%) 37 (77%) 11 (23%) 48 (100%) 31 (65%)
E10.5 45 12 0 (0%) 1 (8%) 1 (8%) 0 (0%) 12 (100%) 2 (17%)
E11.5 23 5 0 (0%) 0 (0%) 0 (0%) 0 (0%) 5 (100%) 0 (0%)
E13.5 10 3 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%)

% of the CKO embryos showing the respective anomaly was shown in parenthesis