Table 1. Study design of ximelagatran exposure study.

Animal groups	Ximelagatran 120 μmol/kg/day
Wild type	n = 10	(5 male, 5 female)
DR7xhCD4	n = 9	(5 male, 4 female)
DR7	n = 9	(4 male, 5 female)
DQ2xhCD4	n = 7	(4 male, 3 female)

Animals were dosed orally, once daily, with ximelagatran for 28 consecutive days. Blood samples were taken at day -1, 14, and 29.