. Author manuscript; available in PMC: 2017 Sep 21.

Published in final edited form as: J Am Chem Soc. 2017 May 31;139(23):7864–7871. doi: 10.1021/jacs.7b02232

Table 1.

Ortho Borylation of Substituted Phenols with B₂pin₂^a

For details, see the SI; yields are isolated.

Entry 1a was obtained in 74% yield on a 2 g scale using 1.5 mol % Ir-catalyst, 3.0 mol % dtbpy, and 0.7 equiv of B₂pin₂.

The Bpin product was converted to the BF₃K salt for isolation.

Conversion and isomer ratio based on GC-FID.

Approximately 18% diborylated product was observed.