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. 2017 Sep 21;12(9):e0185131. doi: 10.1371/journal.pone.0185131

Fig 1. Time-dependent changes in (A) fecal calprotectin (FC), (B) two-item patient-reported outcome (PRO2) and physician’s global assessment (PGA) score from Mayo score, partial Mayo score (PMS), and Lichtiger clinical activity index (CAI) during the first 4 weeks of remission induction treatment.

Fig 1

Each circle shows the mean value of week 4-clinical responders (open circle with solid line) and non-responders (filled circle with dotted line) at each time point. Statistical significance was determined by a Wilcoxon signed-rank test. *p<0.05 compared to the baseline of week 4-clinical responder.