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. 2017 Sep 21;12(9):e0185131. doi: 10.1371/journal.pone.0185131

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© 2017 Toyonaga et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 4 — (A) Within-day variability of fecal calprotectin (FC) in 4 patients with active UC. Three of 4 patients provided fecal samples before (open box) and a week after remission induction treatment (filled box). (B) FC at different times in a single day. (C) Correlation between 2 samples collected from different parts of each feces. Statistical significance in FC among sample collection times was determined by Friedman’s test with post-hoc analysis of Dunn’s multiple comparison test. Pearson’s correlation coefficient was used to analyze correlation in FC between 2 separate samples from each feces. M, morning; B, breakfast; L, lunch; D, dinner.